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CELL & GENE THERAPY INSIGHTS

On demand webinars

Commercializing cell and gene therapies: Navigating complex commercial readiness hurdles for a successful product launch

Commercializing cell and gene therapies: Navigating complex commercial readiness hurdles for a successful product launch

Seth Brittle
4 June 2023
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Analyzing full and empty AAV capsid ratio in less than 5 minutes

Analyzing full and empty AAV capsid ratio in less than 5 minutes

Zoe Anderson-Jenkins
15 April 2023
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Focus on allogeneic CAR-Ts manufacturing challenges and solutions

Focus on allogeneic CAR-Ts manufacturing challenges and solutions

M Langtry, A Sargent, B Baghbaderani
15 March 2023
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How to monitor protein impurities to ensure consistent cell and gene therapy products

How to monitor protein impurities to ensure consistent cell and gene therapy products

13 July 2022
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Simplifying GMP CAR-T and CAR NK cell therapy manufacturing processes

Simplifying GMP CAR-T and CAR NK cell therapy manufacturing processes

M Luevano, X Wang, S Fricke et al.
9 June 2022
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Strategies for Developing a Stem Cell Therapy and Lessons learned from an Early Phase Trial of an MSC-based Therapy for Septic Shock Patients

Strategies for Developing a Stem Cell Therapy and Lessons learned from an Early Phase Trial of an MSC-based Therapy for Septic Shock Patients

8 December 2021
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Test Webinar 2 - Elisa

Test Webinar 2 - Elisa

31 May 2021
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Test Webinar 1

Test Webinar 1

30 April 2021
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Large-scale LVV production: from industry-leading process development to high quality GMP vector

Large-scale LVV production: from industry-leading process development to high quality GMP vector

25 February 2021
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Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

Exploring the capabilities of a versatile, novel, automated closed system for cell and gene therapy manufacturing

16 February 2021
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Fitting product to process: raw materials customization for cell therapy manufacturing success

Fitting product to process: raw materials customization for cell therapy manufacturing success

J Tomtishen III, L Clarke, PhD, L Belcastro et al.
11 February 2021
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Supporting development of mRNA-based therapies by addressing large scale purification challenges

Supporting development of mRNA-based therapies by addressing large scale purification challenges

9 February 2021
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Breaking barriers in viral vector titer analysis speed, volume, and data quality

Breaking barriers in viral vector titer analysis speed, volume, and data quality

R Durham, J Stanta, K Hanson et al.
27 January 2021
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Focusing on donor characteristics and efficient selection to improve allogeneic cell therapy outcomes

Focusing on donor characteristics and efficient selection to improve allogeneic cell therapy outcomes

M Maiers, B Aftab, D Gibson et al.
21 January 2021
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Case study: Optimization of lentiviral vector production from early stages to GMP

Case study: Optimization of lentiviral vector production from early stages to GMP

C Wartel-Weill, N Elizalde, R Lopez de Maturana
19 January 2021
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Raw materials of biological origin: navigating regulatory requirements for cell therapies

Raw materials of biological origin: navigating regulatory requirements for cell therapies

Marlin Frechette, Dominic Clarke
13 January 2021
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Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

Streamlining CAR-T manufacture: reducing complexity and improving robustness through acoustic cell processing

K Lannon, B Ross-Johnsrud, M Li et al.
9 December 2020
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The right time to move to an automated manufacturing system like the Cocoon platform: the when, the why, and the how

The right time to move to an automated manufacturing system like the Cocoon platform: the when, the why, and the how

Test Name
3 December 2020
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Innovative capillary electrophoresis techniques for gene therapy R&D

Innovative capillary electrophoresis techniques for gene therapy R&D

Chris Heger, Julie Wei, PhD
1 December 2020
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Scalable AAV manufacturing – Addressing challenges across the workflow

Scalable AAV manufacturing – Addressing challenges across the workflow

K Thompson, C Liu, J Li et al.
29 October 2020
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Evolving the role of gene editing in cell therapy

Evolving the role of gene editing in cell therapy

J Frampton, T Thwaites, T Meissner
6 October 2020
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The multi-modal manufacturing movement - you don't need to know the future to be ready for it

The multi-modal manufacturing movement - you don't need to know the future to be ready for it

Peter Walters, Noel Maestre
30 September 2020
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Scalable commercial manufacturing: a key strategic element for success of next generation exosome-based cell-free therapies

Scalable commercial manufacturing: a key strategic element for success of next generation exosome-based cell-free therapies

Behzad Mahdavi, Senthil Ramaswamy
24 September 2020
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Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics

Optimizing antibody discovery strategy for clinical success of next-gen immuno-oncology therapeutics

P Ott, I Roodink, N Senutovitch
23 September 2020
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Get your assay in gear – removing analytical bottlenecks on the path to clinical readiness

Get your assay in gear – removing analytical bottlenecks on the path to clinical readiness

Ian Gaudet
8 September 2020
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Identifying the critical factors for commercial-scale viral vector process development and manufacturing

Identifying the critical factors for commercial-scale viral vector process development and manufacturing

B Baghbaderani, X Swanson, S Sanyal
26 August 2020
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Realizing flexible automation – Closing gaps to meet industry needs

Realizing flexible automation – Closing gaps to meet industry needs

K Niss, S Thompson, M Lowdell
12 August 2020
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Size matters: ensuring donor pool sustainability and cell therapy supply chain success when scaling up and out

Size matters: ensuring donor pool sustainability and cell therapy supply chain success when scaling up and out

C Learn, A Agarwal, R Hornung
6 August 2020
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Scalable and efficient AAV production process with new Fibro chromatography technology

Scalable and efficient AAV production process with new Fibro chromatography technology

L Adamson-Small, M Lundgren, P Guterstam
30 July 2020
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Manufacturing of endogenous, non-engineered, antigen specific T cells against tumor targets

Manufacturing of endogenous, non-engineered, antigen specific T cells against tumor targets

Ali Mohamed, Megan Ciarlo
14 July 2020
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Challenges of cell collections for cell therapy manufacturing: what do we want in the bag?

Challenges of cell collections for cell therapy manufacturing: what do we want in the bag?

E Valdez, J Beltzer, S Soni et al.
24 June 2020
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Enabling the industrialization of human induced pluripotent stem cell-based therapies

Enabling the industrialization of human induced pluripotent stem cell-based therapies

K Panchalingam, I Friedrich Ben-Nun, M Langtry
4 June 2020
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AAV downstream processing for industrial scale production – moving towards commercial manufacturing

AAV downstream processing for industrial scale production – moving towards commercial manufacturing

Orjana Terova, Mikhail Goldfarb
20 May 2020
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From vein to vein: how starting material quality impacts the manufacturing and success of next-generation therapies

From vein to vein: how starting material quality impacts the manufacturing and success of next-generation therapies

C McClain, M Giedlin, B Baghbaderani et al.
7 May 2020
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Stable AAV producer cell lines: elevating vector manufacturing

Stable AAV producer cell lines: elevating vector manufacturing

Silke Wissing
5 May 2020
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Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Advances in gene therapy delivery: next-generation transfection reagent for large-scale AAV manufacturing

Mathieu Porte, Malik Hellal
29 April 2020
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Scaling up viral vector manufacturing with adherent and suspension cell cultures

Scaling up viral vector manufacturing with adherent and suspension cell cultures

C Glover, R Legmann, S Gupta
21 April 2020
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Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Lentiviral vector process to accelerate cell and gene therapy clinical development and commercialization

Kevin Beck
16 April 2020
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Enabling new cell therapies with GMP-compliant multiparametric cell sorting

Enabling new cell therapies with GMP-compliant multiparametric cell sorting

S Elliman, I Lai, S Pelletier et al.
18 March 2020
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Ensuring source material consistency and continuity for commercialization of advanced therapies

Ensuring source material consistency and continuity for commercialization of advanced therapies

D Clarke, A Shaw, C Good
12 March 2020
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Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Development and validation of quantitative real-time PCR for the detection of residual HEK-293 host cell DNA

Kara Norman
27 February 2020
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Multi-modal facilities: delivering flexible, future-proof ATMP manufacturing

Multi-modal facilities: delivering flexible, future-proof ATMP manufacturing

Emily Thompson, Noel Maestre
12 February 2020
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Scaling up and out: developing a commercial supply chain strategy to successfully deliver next-generation therapies

Scaling up and out: developing a commercial supply chain strategy to successfully deliver next-generation therapies

T Tripp, J Aho, P Niedzwiedz
6 February 2020
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Capsid titre quantification for AAV-based therapeutics

Capsid titre quantification for AAV-based therapeutics

John Chappell, Tomasz Witkos
30 January 2020
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Collaborative development of a new fill/finish instrument

Collaborative development of a new fill/finish instrument

A Schlinker, C Wegener, D Smith et al.
28 January 2020
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A pragmatic approach to the buy vs build manufacturing dilemma

A pragmatic approach to the buy vs build manufacturing dilemma

N Haderbache, C Houts, J Phillips
16 January 2020
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Combining state-of-the-art production, purification and analytics to optimize AAV manufacturing for clinical and commercial gene therapies

Combining state-of-the-art production, purification and analytics to optimize AAV manufacturing for clinical and commercial gene therapies

B Pence, R Snyder, K Torchilin
10 December 2019
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In-depth case study webinar: how MolMed achieved large-scale GMP production of LV and RV Vectors

In-depth case study webinar: how MolMed achieved large-scale GMP production of LV and RV Vectors

Giuliana Vallanti, Clive Glover
4 December 2019
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Key steps to industrialize your process and de-risk your pathway to commercialization in cell and gene therapy

Key steps to industrialize your process and de-risk your pathway to commercialization in cell and gene therapy

Behnam Baghbaderani
21 November 2019
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Meeting the scalability challenge of downstream viral vector purification

Meeting the scalability challenge of downstream viral vector purification

S Brittle, S Merino, X Fu et al.
12 November 2019
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Let’s talk integration

Let’s talk integration

N Bauer, M Dudley, J Ellis et al.
29 October 2019
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Rapid mycoplasma PCR QC testing for cell and gene therapies

Rapid mycoplasma PCR QC testing for cell and gene therapies

Renate Rosengarten, Angeliki Grammenos
24 October 2019
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Moving towards decentralized manufacturing of cell and gene therapy products through automation

Moving towards decentralized manufacturing of cell and gene therapy products through automation

I Johnston, N Medcalf, Á Urbano-Ispizua et al.
17 October 2019
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A bespoke solution to cell therapy manufacturing: the Cocoon platform

A bespoke solution to cell therapy manufacturing: the Cocoon platform

26 September 2019
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A lens on the final formulation and fill & finish process: considerations for process automation and device development

A lens on the final formulation and fill & finish process: considerations for process automation and device development

K Massey, M Covington, D Sethi
18 September 2019
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No room for error: preparing for inevitable variability in the cell and gene therapy supply chain

No room for error: preparing for inevitable variability in the cell and gene therapy supply chain

J Margolis, L Fox, R Hornung et al.
5 September 2019
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Accelerating advancement in gene therapy by improving downstream purification of viral vectors

Accelerating advancement in gene therapy by improving downstream purification of viral vectors

Orjana Terova, Hetal Brahmbhatt
27 August 2019
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Optimizing the workflow for therapeutic viral vectors – upstream and downstream

Optimizing the workflow for therapeutic viral vectors – upstream and downstream

S Hoover, L Chan, F Bellintani
18 July 2019
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Closing the production gap in gene therapy – A scalable helper virus-free AAV production platform

Closing the production gap in gene therapy – A scalable helper virus-free AAV production platform

N Faust, C Glover, A Topping et al.
11 July 2019
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NextGen now - Delivering tomorrow’s facilities today

NextGen now - Delivering tomorrow’s facilities today

Marc Pelletier, Ryan McDonough
25 June 2019
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Implementation of biopreservation best practices to address a critical component of cell and gene therapy manufacturing

Implementation of biopreservation best practices to address a critical component of cell and gene therapy manufacturing

Alireza Abazari
18 June 2019
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Enabling the next level of pluripotent stem-cell based therapies, from bench to commercialization

Enabling the next level of pluripotent stem-cell based therapies, from bench to commercialization

Puspa Pandey, Fan Yang
13 June 2019
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The power of ultra-high content and 3D imaging for the identification and characterisation of new CAR-T cell targets

The power of ultra-high content and 3D imaging for the identification and characterisation of new CAR-T cell targets

Olaf Hardt, Uwe Schroeer
22 May 2019
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Gaining critical characterization insights for development of CAR-T therapies for solid tumors

Gaining critical characterization insights for development of CAR-T therapies for solid tumors

T Laskowski, J O’Rourke, J Krishnamurthy
16 May 2019
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Using patient outcomes data to inform and advance the development of emerging cell and gene therapies

Using patient outcomes data to inform and advance the development of emerging cell and gene therapies

D Henke, C Wilfong, M Pasquini
9 May 2019
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Optimizing process development to simplify manufacturing scale up of therapeutic viral vectors

Optimizing process development to simplify manufacturing scale up of therapeutic viral vectors

C Lorenzo, V Kedinger, R Legmann et al.
17 April 2019
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Planning for success: emerging GMP-grade raw materials & technologies for cell therapy

Planning for success: emerging GMP-grade raw materials & technologies for cell therapy

S Kevlahan, L Fox, A Herrero et al.
27 March 2019
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Critical components for developing and managing expansive, high-performing collection networks

Critical components for developing and managing expansive, high-performing collection networks

A Hines, R Smith, J Vitale et al.
14 March 2019
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Designing GMP-friendly cell and gene therapy manufacturing processes

Designing GMP-friendly cell and gene therapy manufacturing processes

M Papadimitrious, X Wang, B Murphy
6 March 2019
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Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

Managing starting material stability to maximize manufacturing flexibility and downstream efficiency

Dominic Clarke, David Smith
21 February 2019
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Made-for-purpose manufacturing solutions - The key to commercialization

Made-for-purpose manufacturing solutions - The key to commercialization

N Bauer, B Dutra, Leslie
31 January 2019
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Addressing the challenges of preserving cell and gene therapies

Addressing the challenges of preserving cell and gene therapies

Q Rafiq, A Schlinker, D Maier
18 January 2019
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Evaluation of Poros AAVX Pan-Affinity Resin for rAAV purification and cGMP Manufacturing

Evaluation of Poros AAVX Pan-Affinity Resin for rAAV purification and cGMP Manufacturing

Daniel Hurwit
18 December 2018
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Real-world insights into automated solutions for cell & gene therapy bioprocessing

Real-world insights into automated solutions for cell & gene therapy bioprocessing

B Levine, G Bauer, J Beltzer
12 November 2018
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Scalable, helper virus-free AAV production with stable CAP-GT producer cell lines

Scalable, helper virus-free AAV production with stable CAP-GT producer cell lines

Nicole Faust
8 November 2018
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Latest advances in automated platforms for autologous cell & gene therapy manufacturing

Latest advances in automated platforms for autologous cell & gene therapy manufacturing

E Abraham, D Kuijstermans, Y Shi
25 October 2018
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Strategies to relieve the burden on apheresis & collection centers

Strategies to relieve the burden on apheresis & collection centers

A Hines, G Whitehead, H Steinmetz
11 October 2018
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Making it happen: the road to commercial scale cell therapy manufacturing

Making it happen: the road to commercial scale cell therapy manufacturing

Y Levinson, T Richardson, I Friedrich Ben-Nun
27 September 2018
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Development of a purification step for several AAV serotypes using POROS™ CaptureSelect™ AAVX affinity chromatography

Development of a purification step for several AAV serotypes using POROS™ CaptureSelect™ AAVX affinity chromatography

Magali Toueille
19 July 2018
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Standardized techniques for navigating the cell and gene therapy supply chain

Standardized techniques for navigating the cell and gene therapy supply chain

Jamie Margolis, Mark Dudley
10 July 2018
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Advances in CAR-T manufacture – Bridging the commercialization gaps

Advances in CAR-T manufacture – Bridging the commercialization gaps

I Johnston, K Roy, G Russotti
28 June 2018
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Development & manufacture of next-generation viral vectors for gene therapy

Development & manufacture of next-generation viral vectors for gene therapy

Anandita Seth
20 June 2018
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Challenges of cell therapy manufacturing: automation and disposables – the hand and the glove

Challenges of cell therapy manufacturing: automation and disposables – the hand and the glove

Natasha Boghosian, Brian Hanrahan
10 May 2018
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Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture

Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture

J Brown, M McIntyre, C Simpson et al.
17 April 2018
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Meeting scalability challenges for autologous cell-based manufacturing with automated closed-system solutions

Meeting scalability challenges for autologous cell-based manufacturing with automated closed-system solutions

Giulia Detela
8 March 2018
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GMP raw materials for cell therapy manufacture: what, when and how?

GMP raw materials for cell therapy manufacture: what, when and how?

J Stanton, J Tomtishen III, D Wotta et al.
22 February 2018
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Commercial-scale viral vector manufacture: technical challenges & strategic implications

Commercial-scale viral vector manufacture: technical challenges & strategic implications

M Kelly, C Glover, R Snyder
14 February 2018
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Case studies in cell & gene therapy process optimization

Case studies in cell & gene therapy process optimization

David DiGiusto, Alaina Schlinker
18 January 2018
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Built to scale: strategic considerations to meet production demands in cell and gene therapy

Built to scale: strategic considerations to meet production demands in cell and gene therapy

S Ward, I Gaudet, H Embree
9 January 2018
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Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market

Cell & Gene Therapies for Rare Diseases: Navigating the Pathway to Market

S Kili, G MacKay, S Washer
19 December 2017
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Automation of cell and gene therapy manufacturing: from vein to vein

Automation of cell and gene therapy manufacturing: from vein to vein

Q Rafiq, A Brown, A Chandra et al.
15 November 2017
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Cell & gene therapy manufacturing: key factors influencing manufacturing business models

Cell & gene therapy manufacturing: key factors influencing manufacturing business models

B Nelsen, K Warren, A Dulgar-Tulloch et al.
31 October 2017
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Optimizing supply chain design to ensure commercial success - The journey is as important as the destination

Optimizing supply chain design to ensure commercial success - The journey is as important as the destination

Simon Ellison, Kristen Franklin
12 September 2017
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Addressing the critical bottlenecks in the cell & gene therapy manufacturing pathway

Addressing the critical bottlenecks in the cell & gene therapy manufacturing pathway

P Zandstra, D Baksh, K Roy et al.
21 June 2017
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Advances in preserving, storing and managing the supply chain

Advances in preserving, storing and managing the supply chain

S Ellison, F Meacle, D Clarke
24 May 2017
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The latest developments in CAR-T cell manufacturing

The latest developments in CAR-T cell manufacturing

Isabelle Riviere
27 April 2017
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“One Word: Plastics” – The Role of Material Science in Cell Therapy Manufacturing

“One Word: Plastics” – The Role of Material Science in Cell Therapy Manufacturing

Natasha Boghosian, Katie Campbell
4 April 2017
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Advances in viral vector technology: Anc-AAV & evolutionary guided vector design

Advances in viral vector technology: Anc-AAV & evolutionary guided vector design

Luk Vandenberghe, Dirk Grimm
28 February 2017
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Automation of cell & gene therapy manufacture: challenges, options & opportunities for innovation

Automation of cell & gene therapy manufacture: challenges, options & opportunities for innovation

Q Rafiq, B Hanrahan, B Mistry et al.
7 December 2016
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